The centre of Heraklion city is defined by the Venetian walls, which is the largest fortification of the eastern Mediterranean area and one of the most important monuments of the city. The historic centre of Heraklion has gone through numerous changes over the centuries and has been influenced and enriched by 5 + 1 cultures: Minoans, Romans, Byzantines, Arabs, Venetians and Turks have lived here, leaving their mark on the history, culture and architecture of the city.